Yes, it is possible to remove or change an IP address on an interface.
For example:
# cmsh
% device use node001
% interfaces
% use eth1
To clear the IP address:
% clear ip
To set a new IP address:
% set ip 10.141.0.X
Finally commit the change:
% commit
Once the above change is complete, you will need to reboot the compute node for the change to take affect.